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Risks of Testicular Cancer
Testicular cancer is an abnormal growth in a manís
testicles. Inside the scrotal sac resides to
testis. These are egg like organs that are responsible for
hormonal regulation and production of sperm. When an abnormal
growth appears in the testis, usually one, it is called testicular
cancer.
There are several different types of testicular cancer that can affect
men. The difference in types is related to the type of cell
that has become cancerous. The different cells have different
survival rates and treatment protocols.
However, there are certain risks of testicular cancer that
arenít related to either cell type or treatment.
The risk factors that are now known to be associated with developing
testicular cancer can be attributed to physiology, history, disease
processes, age, race and size.
One of the main risk factors for testicular cancer is a condition
called cryptorchidism, or undescended testicles. In this
condition men are born with a testicle or two that doesnít
come down into the scrotal sac. They remain deep within the
abdomen or get stuck in the groin area. Most of the time the
testicle will descend by the time the child is 1 but if it remains
undescended the physician may recommend an orchiopexy to bring the
testicle down into the scrotal sac.
If the testicle remains undescended the heat of the body kills the
sperm. It also raises the risk of developing testicular
cancer. Interestingly up to 25% of the cancers happen in the
testicle that is descended which leads researchers to believe that it
isnít the testicle in the body that causes the cancer but
rather there is something else that leads to both the undescended
testicle and the development of testicular cancer.
If a man has a family history of testicular cancer he is also at a
higher risk than the general public. There is also a greater
risk for his sons or brothers. There has also been
some evidence to suggest than men who are infected with HIV are at an
increased risk. There have been no other infections that are
associated with the development of this condition.
Other risks of testicular cancer include cancer of the other testicle
and cancer in situ. If a man has cancer in one testicle he
has a 3 ñ 4% greater chance of getting cancer in the one
testicle that wasnít removed. Cancer in situ is a
condition that doesnít produce a mass or cause symptoms but
instead is found when a testicle is removed for cryptorchidism or is
found during a workup for infertility. It isnít
clear as to how many men may have undiagnosed CIS before developing
testicular cancer.
In a study of over 30,000 men who had semen analysis between 1963 and
1995 researchers found that those men who had an abnormal semen
analysis also had a greater risk of developing testicular
cancer. It appeared that low semen quality may be associated
with an increase in extragonadal germ cell tumors.
Racial background also appears to have an impact on the development of
testicular cancer. It appears that Caucasians have a 5-10
times greater likelihood of developing the cancer over African
Americans and a twice greater risk than Asian Americans.
Researchers also found that 90% of these cancers appear between the
ages of 20 and 54 but that it can affect men of any age ñ
including infants and the elderly. Interesting there have
also been one or two studies that have linked testicular cancer to men
who are taller in stature but these results have to be further tested
and evaluated.
The risks of testicular cancer are spread across the general population
of men. However, because of the recent improvements in
diagnosis and early treatment protocols the outlook isnít
nearly as grim as it was just 10 years ago.
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